Date(s) - 04/10/2020
University of Coimbra
Categories No Categories
As agreed during the kick off meeting hold in Santiago de Compostela on June 19th 2019, Coimbra was the city chosen for the next reunion. The meeting was held at the University of Coimbra on October 4th, 2019, and two work packages were discussed during this meeting.
On the one hand, the first work package was about the “Development of novel diagnostic methods for the early diagnosis of AD” which aim is to develop innovative diagnostic methods for AD, including both in-vitro and in-vivo methods that may contribute to patient stratification (mild cognitive impairment vs AD and AD and different tauopathies).
Among the specific objectives of this project, the followings can be highlighted:
- The development of novel immunoassays for the detection of Tau oligomers in several samples from patients, namely, CSF and serum. An automatized system developed by STABVIDA will be tested.
- Proof-of-concept study for the development of novel PET Tracers against Tau oligomers.
- Development of novel MRI and PET imaging biomarkers based on image processing techniques.
On the other hand, the second work package discussed was the “Development of novel therapeutic and diagnostic approach for management of stroke patients” which aims is to promote translational research to test in vitro and in vivo models from the diagnostic and therapeutic utility of the innovative technologies and drugs developed by neuroATLANTIC partners.
Among the specific objectives of this project, the following can be highlighted the:
- The development of novel therapeutic compounds for new treatments for cerebrovascular diseases tested in in vitro and in vivo models.
- Proof-of-concept study for the development of novel MRI/TC software for the selection of stroke patients for recanalization approaches.