Center for Cooperative Research in Biomaterials CICbiomaGUNE
Brief description of the entity
The Center for Cooperative Research in Biomaterials- CIC biomaGUNE, located in San Sebastián (Spain), was officially opened in December 2006 and is a non-profit research organization created to promote scientific research and technological innovation at the highest levels in the Basque Country. CIC biomaGUNE has established a state of the art research program at the interface between the chemical, biological and physical sciences with a main emphasis on molecular scale properties and applications of biological nanostructures. The main research lines deal with the design, preparation and characterization of biofunctional nanostructures to be used in the study of biological processes.
Activities and services offered
The Molecular and Functional Imaging Platform of CIC biomaGUNE, designed and built to become a reference facility in the field of pre-clinical imaging, offers state of the art resources in: – Radiochemistry: Equipped with a cyclotron capable of producing positron-emitting isotopes, automatic synthesis systems and quality control equipment, enables the production of tailored radiotracers to approach in vivo studies. – Nuclear imaging: Equipped with PET-CT, SPECT-CT and PET-SPECT-CT cameras. – MRI: with two high-field scanners (7.0 T and 11.7 T), operating at proton resonance frequencies of 300 and 500MHz, respectively. – Animal facility, AAALAC-accredited, of exclusive dedication and with capacity for 500 mice and 400 rats housed in individually ventilated cages. The design of the facility allows executing multimodal and longitudinal studies in different disease areas.
The differentiating value
Having all the imaging modalities together, close to a cyclotron and a radiochemistry lab and with independent management.
Your role in neuroATLANTIC project
Investigate, using in vivo imaging modalities, different pathophysiological aspects of Alzheimer disease and ischemia in animal models. To develop new imaging biomarkers for the investigation of such diseases.
The results you expect to achieve
Develop new imaging biomarkers Gain knowledge about the temporal evolution of physiopathological aspects of Alzheimer disease and ischemia, which could pave the way towards the development on diagnostic or therapeutic tools
Your thoughts about the importance and the opportunity this project represents and your main goal by participating in it
The project represents a great opportunity to: (i) establish synergies with complementary groups and approach ambitious studies in a coordinated fashion; and (ii) create capacities to tackle more challenging studies in the future
Your thoughts about the impact that this project will have on the ecosystem
The project can bring new tools for the management of two diseases with high incidence and socio-economical burden.
Radiochemistry and Nuclear Imaging Group
- Location: Parque Científico y Tecnológico de Gipuzkoa. Paseo Miramón 182, 20014 Donostia / San Sebastián, Gipuzkoa. Spain.
- URL: https://www.cicbiomagune.es/